Beta-alanine: The meta-analysis – 18 trials, still a marginal effect

I’ve always thought a meta-analysis on beta-alanine was a good idea. So many of the trials have been underpowered, that it felt like weren’t getting anywhere fast. I wanted to be the one to do it, but life circumstances have kept me from focusing on much other than my main career. So it was a pleasant surprise to see that someone else had the same idea.

With just 11 weeks left before my exams though, I’m going to keep this blog entry brief. Read More...

Beta-alanine redux: Same question, still no answer. But they still recommend you take it.

It’s been three years since I’ve written about beta-alanine. I do monitor the literature from time to time to see what’s new in the BA research world. But really, there isn’t anything new. There still is no definitive answer that BA does anything meaningful. The latest BA study not only failed to find anything meaningful, but also failed to plan to find anything meaningful, allowing the gods of statistical probability to decide if the fruits of their labour would be met with reward.

Kern BD, Robinson TL. Effects of beta-alanine supplementation on performance and body composition in collegiate wrestlers and football players. Journal of Strength and Conditioning Research, 25(7):1804-1815, 2011. Read More...

More is not better–when statistics turn bad (it’s just not as entertaining as when animals do)

As with everything, more is not usually better. In statistics, more actually makes you more prone to being accidentally wrong (or, in statistics-lingo, spurious). Today, I’d like to talk about a basic concept that is taught to students in their introductory statistics courses (and hence, you would think, most researchers): The effect of multiple significance testing. Read More...

Beta-alanine revisited: Failing to plan, or planning to fail?

In the past 2.5 years, a few more studies on beta-alanine have emerged. As I’ve written before, my goal isn’t to become the anti-beta-alanine blogger, but I do feel that watching this supplement develop from its relative inception to its current state does provide an interesting prototype for how similar products develop a strong following despite the limitations on the research available to support (or not support) its use. Read More...

Why I’m not writing about beta-alanine lately

I’ve had a more than a few requests to write more reviews on beta-alanine, since it seems to be all the rage. It is so much the rage lately, that I get more hits on my reviews of the three beta-alanine studies than anything else, by a very large margin. The reviews have been linked by so many people that this blog is on the third page of a Google search for the term “beta alanine” (and this search includes hits from ALL of the supplement sites that SELL beta-alanine), and the FIRST hit when you search Google for “beta alanine studies”. The. First. Hit. Holy. Crap. Read More...

Beta-alanine: The Harris Study (this is what grad students are actually used for)

I was going to write a review of the Harris study on beta-alanine, but after reading it in detail, I realized it wasn’t a randomized controlled trial at all, but rather a physiological study, with biochemical outcomes, but no “functional” ones. And despite the fact that one of their experiments was a “quasi” randomized controlled trial, I haven’t got a lot to say about it because this was not a study to look at the effectiveness of BA, but rather to profile its effects. On the up side, there was a rather nice recipe for chicken broth–which is where they got their beta-alanine for one of the experimental groups: Read More...

Another beta-alanine study. Don’t buy the hype.

Some day, I’m going to preface a review with a sentence like, “Today’s study was really well done. I was impressed by the comprehensiveness of the reporting, the concise data analysis and the practical relevance of the trial.” Read More...

Beta-alanine vs. um…stuff. No one really wins.

Ok, I’m behind the times. By about 3 months. But you know, it’s ’cause I have to go searching for this stuff all by myself! Maybe we should consider this a bit of catch-up, since the blog was started only a month ago. If you see a good study, or mention of one, send me the freaking reference! Some “cutting edge” blogger I turned out to be, eh… Read More...